Supermicro GPUs: Optimized for AI, HPC, and Enterprise Workloads

Accelerate your most demanding applications with our GPU-optimized server solutions—engineered for scalability and efficiency.

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GPU Solutions for Data-Intensive Workloads

From AI training to 3D rendering, Supermicro delivers unmatched density and performance per watt.

GPU Server

SuperServer SYS-421GU-TNXR | Universal 4U Dual Processor

Ideal for High-Performance Computing, AI/Deep Learning, LLM NLP with 8TB DDR5 memory, 8 PCIe Gen 5.0 slots, flexible networking, 2 M.2 NVMe/SATA, and 6 hot-swap drive bays.

CPU

Dual 5th Gen Intel® Xeon® / 4th Gen Intel® Xeon® Scalable processors

MEM

Slot Count: 32 DIMM slots Max Memory: Up to 8TB 5600MT/s ECC DDR5

HD

Hot-swap : 6x 2.5" hot-swap NVMe/SATA drive bays (6x 2.5" NVMe hybrid)

PCIE

1 PCIe 5.0 x16 LP slot(s) 7 PCIe 5.0 X16 slot(s)

see detailed specification
GPU Server

A+ Server AS-4125GS-TNRT

AI/Deep Learning optimized, supports 8 GPUs, dual AMD EPYC™ 9004 up to 360W, 6TB DDR5 memory, 4 hot-swap NVMe bays, 1 M.2 slot, AIOM/OCP 3.0 support. Ideal for high-performance computing.

CPU

Dual AMD EPYC™ 9004 Series Processors up to 360W TDP

MEM

Slot Count: 24 DIMM slots Max Memory: Up to 6TB 4800MT/s ECC DDR5 RDIMM/LRDIMM

HD

24x 2.5" hot-swap NVMe/SATA/SAS drive bays (4x 2.5" NVMe dedicated)

PCIE

9 PCIe 5.0 x16 FHFL slot(s)

see detailed specification
GPU Server

SuperServer SYS-521GE-TNRT 5U Dual Processor

Meet the GPU SuperServer SYS-521GE-TNRT: A high-performance server with 5th/4th Gen Intel® Xeon® support, 8TB DDR5 memory, 13 PCIe Gen 5.0 slots, AIOM/OCP 3.0, and 8 hot-swap SATA bays. Ideal for data-intensive tasks.

CPU

Up to 64C/128T; Up to 320MB Cache per CPU

MEM

Max Memory (2DPC): Up to 8TB 4400MT/s ECC DDR5 RDIMM

HD

8 x 2.5" Gen5 NVMe/SATA/SAS hot-swappable bays

PCIE

Up to 10 double-width or 10 single-width GPU(s)

see detailed specification
GPU Server

5468A7 8 GPU AI Server with PCIe 5.0

5468A7 is a powerful 4U AI server supporting AMD EPYC™ 9004 processors and the latest PCIe Gen 5.0 architecture. Its 10-card pass-through design significantly reduces CPU and GPU communication latency.

CPU

2x AMD EPYC™ 9004 processors, up to 400W

MEM

24x DDR5 4800MT/s RDIMMs

HD

24x 2.5” SSD, up to 16x NVMe U.2 2x NVMe/SATA M.2

PCIE

11x PCIe 5.0 x16 slots

see detailed specification

Powering Industry Transformations

Deploy cutting-edge GPU solutions with our proven server architectures and liquid cooling options.

AI Model Training

8x NVIDIA H100 per 1U: 12x faster LLM training vs. air-cooled systems
Direct Liquid Cooling: 40% lower power consumption at full load
Petascale Storage: Process 1TB/s of training data with NVMe-oF

Scientific Simulation

4x AMD Instinct MI300X: 5x faster climate modeling vs. CPUs
Supermicro BigTwin®: Scale to 16 GPUs in 4U with unified memory
HPC-as-a-Service: Deploy research clusters in under 1 hour

Expert recommendations for Your Workflow

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Reduce AI training time by up to 40%
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Cut rendering costs by 30%
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Scale compute resources on demand"

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